The paper deals with unsteady inter-porosity flow modeling of underground fluid in a multiple media reservoir. Assuming spherical vugs, symmetrically distributed pressure, negligible inter-porosity flow between matrix and vug systems and centrifugal flow of the fluid from matrix blocks or vugs to fractures, and treating media directly connected with wellbore as the fracture system, we establish and solve a model of unsteady inter-porosity flow for dual and triple porosity media reservoirs. We provide simulated graphs of pressure and pressure derivative log-log type curves, and analyze the transient flow process and characteristics of type curves affected by different parameters. The new type curves of unsteady inter-porosity flow modeling are evidently different in shape and characteristics from those of pseudo-steady inter-porosity flow modeling. The location of dimensionless pressure of unsteady inter-porosity is lower than that of pseudo-steady inter-porosity, which indicates that unsteady inter-porosity flow accelerates an energy supplement during production. Qualitatively, the unsteady inter-porosity flow modeling reduces the classical V-shaped response. We also estimated parameters from well test data in real applications using this model.